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Ctional as long as either of the two MAPKKKs is catalytically active. Although less crucial, the MAPKKK heteromer also appears to contribute to prompt activation of the MAPK cascade upon oxidative stress (Supplemental Figure S2; Shiozaki et al., 1998).FIGURE 2: The Wis4 and Win1 MAPKKKs form a heteromer complex. (A) win1:myc and wis4:myc strains were used to monitor the expression levels of the MA
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Mined intents, 1987?011, percentage with 95 CI, by sexUndetermined 2 909 24.3 (22.8-25.9) 31.7 (30.0-33.4) 28.9 (27.3-30.6) 15.1 (13.8-16.4) 2 909 15.4 (14.1-16.7) 84.6 (83.3-85.9) 1 283 39.4 (36.8-42.1) 43.7 (41.0-46.4) 16.8 (14.8-18.9) 2 014 5.9 (4.9-6.9) 11 (9.6-12.4) 14.3 (12.8-15.8) 68.9 (66.9-70.9) 2 014 13.2 (11.7-14.7) 22.3 (20.5-24.1) 26.7 (24.8-28.6) 37.8 (35.7-39.9) 2 014 10.5 (9.2-11.
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Epartment of Veterans Affairs Merit Review Award, and by funds from Belluck and Fox, LLP New York, New York. We thank the NYU Cancer Institute Genomics Facility for expert assistance with gene expression profiling. 18.19.Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract. GIST pathogenesis is most frequently attributed to gain-offunction mut
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Ctional as long as either of the two MAPKKKs is catalytically active. Although less crucial, the MAPKKK heteromer also appears to contribute to prompt activation of the MAPK cascade upon oxidative stress (Supplemental Figure S2; Shiozaki et al., 1998).FIGURE 2: The Wis4 and Win1 MAPKKKs form a heteromer complex. (A) win1:myc and wis4:myc strains were used to monitor the expression levels of the MA
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Ctional as long as either of the two MAPKKKs is catalytically active. Although less crucial, the MAPKKK heteromer also appears to contribute to prompt activation of the MAPK cascade upon oxidative stress (Supplemental Figure S2; Shiozaki et al., 1998).FIGURE 2: The Wis4 and Win1 MAPKKKs form a heteromer complex. (A) win1:myc and wis4:myc strains were used to monitor the expression levels of the MA
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